Fertility Challenges? 5 Supplements You Haven’t Tried But Should

Fertility Challenges

Are you and your partner experiencing fertility challenges and struggling to conceive? You aren’t alone. We’ve helped thousands of women in their 30s and 40s across the globe conceive with our award-winning Primemester™, the best-kept fertility secret. 

An essential part of the Primemester™ Protocol is the introduction of supplements. After all, a healthy body is the first step towards overcoming fertility challenges and achieving a successful conception and a happy baby full of vitality. If your body is deficient in certain vitamins, or minerals, that might be the culprit preventing you from conceiving. 

In this blog post, we’ll look at some supplements you can consider introducing into your wellness regimen to combat fertility challenges, increase your chances of conception, and prepare your body for pregnancy. 

Pre-Pregnancy & Prenatal Supplements To Increase Fertility

A comprehensive and proactive prenatal supplement should have a blend of vitamins to increase fertility and prepare your body for pregnancy specifically. Opt for supplements that are curated through scientific reasoning, have evidence-based formulations, and are naturally sourced, as low-quality products may contain contaminants and other chemicals that can do more harm than good. 

Fertility challenges are a growing problem in today’s fast-paced society as our reproductive bodies struggle to deal with daily stressors. Our Superbaby Nutraceutical range takes this into consideration with carefully curated formulas in our Prime Pre-Pregnancy & Prenatal and Prime Male supplements, which address this mismatch. Our Superbaby Nutraceuticals range contains naturally occurring ingredients that mimic the composition of a healthy diet consisting of whole, nutrient-dense foods. With a blend of essential, foundational nutrients that fill possible nutrient gaps that may encourage fertility challenges and meticulously chosen vitamins, minerals, and phytonutrients your body craves for fertility and conception. From your primemester to postpartum, Superbaby Nutraceuticals can provide you with the nutrients you need for every stage of your parenthood.

Explore the Superbaby Nutraceutical range for your fertility goals, Mama.

1. Phytonutrients and Fertility Challenges

Our pre-pregnancy supplements, Prime Pre-Pregnancy & Prenatal and Prime Male, which also include many phytonutrients that benefit male and female fertility. Phytonutrients offer you a more potent, bioavailable form of nutrients than those in herbal supplements, which many resort to when looking for natural ways to overcome fertility challenges.

Previously, our consumption of phytonutrients like lutein and lycopene was adequate to support reproductive health (Shao & Hathcock, 2006). However, with the modern diet that’s commonly filled with processed food, our consumption of phytonutrients is significantly decreased, and with it, our reproductive health.

The lack of phytonutrients has been linked to infertility and fetal growth restriction, increasing the risk of diabetes, cardiovascular disease, obesity, and depression in the offspring (Lakshmi et al., 2014). Phytonutrients have also been linked to healthier brain and spinal cord development. For these incredible benefits, Prime Male and Prime Pre-Pregnancy & Prenatal contain essential phytonutrients like lutein, lycopene, resveratrol, wild blueberry, broccoli seed/sprout, citrus bioflavonoids, and more.

High-quality prenatal supplements should also have a generous dose of phytonutrients to increase your fertility and give your baby a headstart in growth and development. 

2. Vitamin D For Fertility Challenges

Getting enough sunshine in our lives doesn’t seem to be everyone’s top priority with the hustle and bustle of everyday life. We are constantly at our desks working, in our homes, or in buildings – rarely do we get to take in a few minutes of our naturally enriching sunshine. I cannot stress enough how essential it is to get your daily dose of vitamin D for your reproductive health.  

While exposure to the sun is our natural source of vitamin D, in the US alone, 42% of adults are deficient in the critical vitamin. This is even more staggering when you take into consideration people of color with higher levels of melatonin (skin pigment), which makes vitamin D absorption from sun exposure even more difficult.  With the global need for vitamin D starkly apparent, it is important to acknowledge its role in your fertility. Here’s how this essential vitamin might help increase fertility. 

2.1 Hormone Regulation

One of vitamin D’s responsibilities is to regulate your hormones like insulin which is critical for blood sugar levels, estrogen, and testosterone, which we know are incredibly important for fertility (Chu et al., 2021). Having balanced hormonal levels is key to successful conception and a comfortable pregnancy. 

2.2 Ovulation

In women, balanced hormones are necessary for the regular and healthy release of mature eggs from the ovaries during ovulation. Hormones such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are responsible for triggering ovulation, and an imbalance can disrupt this process. Studies have shown that Vitamin D works at a cellular level, enhancing ovulation by altering AMH signaling, increasing FSH sensitivity, and boosting progesterone production, ultimately aiding in conception and healthy pregnancy (Várbíró et al., 2022). 

2.3 Regulating The Menstrual Cycle

Hormones, including estrogen and progesterone, control the menstrual cycle. An irregular or absent menstrual cycle can indicate hormonal imbalances, making it difficult to time conception effectively. A study revealed that women with steady cycles had notably higher levels of Vitamin D (Subramanian & Gernand, 2019). On the flip side, lower Vitamin D levels were linked to a whopping 13 times higher chance of having an irregular cycle. This is due to a vitamin D deficiency, which can be connected to lengthened follicular phases, delayed ovulation, and cycles that stretch beyond the usual timeframe.

2.4 Uterine Health

Vitamin D is believed to play a role in maintaining the health of the uterus and the uterine lining. A healthy uterine environment is essential for implantation and a successful pregnancy. Studies show that people with lower vitamin D have lowered levels of progesterone, putting them at risk for miscarriage and other pregnancy complications, more troubling is the risk of uterine fibroids developing (Hajhashemi et al., 2019).

2.5 Polycystic Ovary Syndrome (PCOS)

PCOS is a common condition in women that can disrupt fertility. There has been a considerable link between vitamin D deficiencies and a PCOS diagnosis, however, the cause is still a debated topic (Tran, 2021). Even though we know that vitamin D deficiencies don’t directly cause PCOS some studies suggest that vitamin D supplementation may help improve some of the symptoms of PCOS and enhance fertility in women with this condition (Wu & Lin, 2015).

2.6 Cervical Mucus Production

Hormones impact the production and consistency of cervical mucus, which plays a crucial role in helping sperm reach the egg in the fallopian tube (Riazi et al., 2019). Imbalances can affect the quality and quantity of cervical mucus, hindering sperm movement.

These fertility challenges can all be combated through sufficient vitamin D supplementation, ensuring optimal health, and vitality for your fertile potential and increase your chances for conception. Prime Vitamin D with K1 and K2 provides a high-serum vitamin D dosage that both you and your partner or donor can take advantage of for your fertility and overall health. With the synergistic effects of vitamins K1 and K2, you can leave your worries behind knowing that your body will absorb, metabolize, and use every drop of vitamin D.

Optimize your fertile future with Prime Vitamin D with K1 and K2 today!

3. DHA For Fertility Challenges

DHA, or docosahexaenoic acid, which is an omega-3 fatty acid essential for various aspects of health, including fertility, especially in women. DHA is an important component of cell membranes that plays a role in the female reproductive system, particularly egg quality and the ovaries. Balanced DHA levels are essential to promoting regular, healthy ovulation, and reduces inflammation which is the key to better egg and sperm quality and preventing reproductive aging

In addition, DHA can also increase cervical mucus, which will help transport the sperm to fertilize the egg. That’s not all. Once you’ve conceived, DHA is vital to the development of your baby’s brain and eyes. Healthy DHA levels throughout your pregnancy can help with your baby’s cognitive and visual development (Stanhiser et al., 2022). 

Lastly, it isn’t only about us! DHA also increases male fertility by supporting healthy sperm development and function, so share those supplements with your superbaby daddy. These incredible benefits can be found in our Prime DHA, an incredible source of this vital fatty acid and highly bioavailable – without the presence of unbalancing omega 6s and omega 9s, which are disproportionately present in our modern diet and interfere with fertility outcomes.

Reduce fertility challenges associated with reproductive aging with Prime DHA, Mama!

4. Probiotics For Fertility Challenges

Not all types of bacteria are nasty, and your colon is full of trillions of helpful microorganisms called probiotics. These microscopic warriors go to battle for your body, kicking out invading harmful bacteria and protecting your cells and stomach lining from damage. 

A healthy gut microbiome is essential for a well-functioning immune system that is critical to reproductive health. Our spore-based Prime Probiotic Microbiome Support supplements contain powerful bacterial strains (bifidobacterium and lactobacillus) that aid in fertility and your second genome – your vaginal microbiome. This aids in reducing oxidative stress and inflammation, both of which contribute significantly to egg health, sperm health, uterine health, and fetal health and programming.

Antioxidants are essential to keep the body in balance, fighting off free radicals that we get from our environment. Free radicals are unstable molecules that we get from external sources such as pollution, cigarette smoke, and chemicals (Pham-Huy et al., 2008). 

When we have an overload of free radicals, our bodies go into an oxidative stress state. Prolonged periods of oxidative stress can result in serious illnesses such as cancer, heart disease, Parkinson’s, and Alzheimer’s, and in the realm of fertility – it is a serious threat to reproductive health and can be the potential cause of several fertility challenges (Lobo et al., 2010). 

Probiotics and antioxidants can help bring your body back into balance and reduce stress and inflammation, significantly improving your reproductive health. In addition, keeping a healthy gut also increases the absorption rate of other beneficial vitamins such as magnesium and calcium. 

You can naturally consume probiotics from fermented foods such as kefir, kimchi, sauerkraut, zero-sugar and non-alcoholic kombucha drinks, and non-dairy yogurt (unless your body and DNA do well with dairy). However, a supplement is the easiest way to include adequate probiotics into your diet.

A very important note, Mama. It is safest to consume fermented foods with caution and your obstetrician or gynecologist clearance once you are pregnant. If you prefer to supplement probiotics, you can find carefully considered bacterium strains in our Prime Probiotic Microbiome Support that combats fertility challenges associated with inflammation and oxidative stress, enhancing your reproductive potential.

Protect your fertility with Prime Probiotic Microbiome Support.

4.1 Prebiotics

Now that your gut is full of beneficial bacteria you want to keep there, you’ll need to feed them and keep them happy. Prebiotics are non-digestible fibers and compounds that function as a source of nutrition for the probiotics in you that offer gut-healing properties and combat fertility challenges associated with a disrupted endocrine system. 

You can find prebiotics in many low-glycemic fruits and veggies, such as: 

  • Garlic 
  • Onions
  • Leeks
  • Bananas
  • Asparagus
  • Berries (beware the dirty dozen)
  • Oats
  • Apples
  • Chicory Root
  • Whole grain foods such as barley, wheat, quinoa, and brown rice (in moderation)

5. Folate For Fertility Challenges

Folate, also known as vitamin B9, is a critical fertility and pregnancy nutrient. During the first few weeks of early pregnancy, folate plays a key role in ensuring the health of the neural tube, which eventually develops into the baby’s brain and spinal cord. Folate is essential for the proper closure of the neural tube, which will reduce the risk of congenital disabilities. Our Extra Neural Tube & Chromosomal Care bundle highlights the importance of folate paired with B12 for your future baby’s spinal cord development and chromosomal integrity.

In addition, folate plays a crucial role in DNA synthesis and cell growth, active processes during pregnancy as the body grows and develops. Folate helps produce and maintain new cells, which is particularly important during the rapid cell growth that happens in the early pregnancy stages (Miraglia & Dehay, 2022). By supplementing with folate correctly, you can potentially mitigate fertility challenges by protecting and ensuring the proper development of your future baby and having a safer conception and pregnancy.

Folate supplements come in many forms, but not all forms of folate are equal. Each form of folate varies in quality and bioavailability. Folic acid is the synthetic form of vitamin B9, while folinic acid is a type of folate found in food, which your body must convert to methyltetrahydrofolate. It is recommended to use the most bioavailable form of vitamin B9, 5-methyltetrahydrofolate (5-MTHF), as it is the most effective and can be used by the body immediately after consumption. Our Prime Methylated Folate Extra contains a very valuable form of 5 methyltetrahydrofolate (5-MTHF), so it is immediately bioavailable to be assimilated into your system. 

For your ideal folate formulation, get Prime Methylated Folate Extra and ensure your superbaby’s health.

FPI’s Fertility Supplements: Superbaby Nutraceuticals 

Frustrated that you are having fertility challenges and are struggling to conceive? You aren’t alone, and we’d like to help. 

At the Fertility & Pregnancy Institute (FPI), we have been helping women worldwide conceive healthy babies. I head the Institute, Dr. Cleopatra, a scientist, tenured USC professor, and mom of three who revolutionized the world of fertility biohacking. 

Dr. Cleopatra has received nearly $3 million in grant funding from organizations such as the National Institutes of Health, the National Science Foundation, and the National Institute on Standards Technology. She has been cited in over 1,000 scientific studies in the past five years alone and is a well-respected leader in the fertility field. 

FPI has developed a range of exclusive supplements, all thoroughly researched and designed with utmost care to boost fertility and increase your chance of conception. Visit our online shop and let us help. All our products are whole-food based and medical grade, undergoing strict third-party testing to ensure purity and potency. 

Invest in your fertility and reap the rewards by overcoming fertility challenges with Superbaby Nutraceuticals.

If you prefer a more intimate approach to your fertility, email our support inbox (support@fertilitypregnancy.org) for a friendly chat. We are eager to share our best-kept fertility secret system, the Primemester™. It has helped countless women all over the globe conceive without stress or fuss, and we’re hoping it will help you, too.  


Chu, C., Tsuprykov, O., Chen, X., Elitok, S., Krämer, B. K., & Hocher, B. (2021). Relationship between vitamin D and hormones important for human fertility in reproductive-aged women. Frontiers in Endocrinology, 12, 666687. https://doi.org/10.3389/fendo.2021.666687

D, Lakshmi & Prasanna, N. & R., Baskar. (2014). Phytochemicals from nine plants beneficial for pregnant women. International Journal of Pharmacological Research. 4. 10.7439/ijpr.v4i4.137.

Eske, J. (2019, April 3). What is oxidative stress? Effects on the body and how to reduce. Www.medicalnewstoday.com. https://www.medicalnewstoday.com/articles/324863

Hajhashemi, M., Ansari, M., Haghollahi, F., & Eslami, B. (2019). The effect of vitamin D supplementation on the size of uterine leiomyoma in women with vitamin D deficiency. Caspian Journal of Internal Medicine, 10(2), 125–131. https://doi.org/10.22088/cjim.10.2.125

HealthMatch. (2022, November 30). 42% of americans are deficient in vitamin D. are you at risk? If so, what can you do about it? HealthMatch Ltd. https://healthmatch.io/blog/42-of-americans-are-deficient-in-vitamin-d-are-you-at-risk-if-so-what-can

Hodgdon, K. (2023, June 23). 3 reasons to add a DHA supplement to your fertility routine. Rescripted.com. https://rescripted.com/posts/3-reasons-to-add-a-dha-supplement-to-your-fertility-routine

Lobo, V., Patil, A., Phatak, A., & Chandra, N. (2010). Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy Reviews, 4(8), 118–126. https://doi.org/10.4103/0973-7847.70902

Metcalf, E. (2022, November 27). What are phytonutrients? Types and food sources. WebMD. https://www.webmd.com/diet/phytonutrients-faq

Miraglia, N., & Dehay, E. (2022). Folate supplementation in fertility and pregnancy: The advantages of (6s)5-methyltetrahydrofolate. Alternative Therapies in Health and Medicine, 28(4), 12–17. https://pubmed.ncbi.nlm.nih.gov/35653630/

OmegaQuant. (2022, July 28). Vitamin D and menstrual cycle regularity. OmegaQuant. https://omegaquant.com/vitamin-d-and-menstrual-cycle-regularity/

Pham-Huy, L. A., He, H., & Pham-Huy, C. (2008). Free radicals, antioxidants in disease and health. International Journal of Biomedical Science : IJBS, 4(2), 89–96. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614697/

Riazi, H., Ghazanfarpour, M., Taebi, M., & Abdolahian, S. (2019). Effect of vitamin D on the vaginal health of menopausal women: A systematic review. Journal of Menopausal Medicine, 25(3), 109. https://doi.org/10.6118/jmm.19194

Shao, A., & Hathcock, J. N. (2006). Risk assessment for the carotenoids lutein and lycopene. Regulatory Toxicology and Pharmacology, 45(3), 289–298. https://doi.org/10.1016/j.yrtph.2006.05.007

Stanhiser, J., Jukic, A. M. Z., McConnaughey, D. R., & Steiner, A. Z. (2022). Omega-3 fatty acid supplementation and fecundability. Human Reproduction (Oxford, England), 37(5), 1037–1046. https://doi.org/10.1093/humrep/deac027

Subramanian, A., & Gernand, A. D. (2019). Vitamin D metabolites across the menstrual cycle: A systematic review. BMC Women’s Health, 19(1). https://doi.org/10.1186/s12905-019-0721-6

Tran, D. (2021, December 9). PCOS: Daily dose of vitamin D. Byrdine F. Lewis College of Nursing and Health Professions. https://lewis.gsu.edu/2021/12/09/pcos-daily-dose-of-vitamin-d/

Várbíró, S., Takács, I., Tűű, L., Nas, K., Sziva, R. E., Hetthéssy, J. R., & Török, M. (2022). Effects of vitamin D on fertility, pregnancy and polycystic ovary syndrome-a review. Nutrients, 14(8), 1649. https://doi.org/10.3390/nu14081649

Wu, M.-H., & Lin, M.-W. (2015). The role of vitamin D in polycystic ovary syndrome. Indian Journal of Medical Research, 142(3), 238. https://doi.org/10.4103/0971-5916.166527

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